Technical papers

R. Hoffmann, H. Lüdtke.

In: FM Camacho, A Tosti(eds); Montagna Trichology Diseases of the pilosebaceus follicle Vol I (2016), Page 177-183 Download

R. Hoffmann, H. Lüdtke, M. Hoffman-Wecker, B. J. Hughes-Formella.
Digital imaging for measuring of hair growth on the human scalp
In: E. Berardesca et al. (eds); Non Invasive Diagnostic Techniques in Clinical Dermatology (2014), Page 413-422

Peer reviewed articles where the TrichoScan® has been used

Blume-Peytavi U, Issiakhem Z, Gautier S, Kottner J, Wigger-Alberti W, Fischer T, Hoffmann R, Tonner F, Bouroubi A, Voisard JJ
Efficacy and safety of a new 5% minoxidil formulation in male androgenetic alopecia: A randomized, placebo-controlled, double-blind, noninferiority study.
J Cosmet Dermatol. 2018 Apr 16. doi: 10.1111/jocd.12541. Link

J Gassmueller, E Rowold, T Frase and B Hughes-Formella
Validation of TrichoScan ® technology as a fully-automated tool for evaluation of hair growth parameters.
Eur J Dermatol (2009) Feb (12): 224-31  Download

J Gassmueller, R Hoffmann and A Webster
Topical fulvestrant solution has no effect on male and postmenopausal female androgenetic alopecia: results from two randomized, proof-of-concept studies.
British Journal of Dermatology (2008) 158, 109–115

R Hoffmann
A 4-month, open-label study evaluating the efficacy of eflornithine 11.5% cream in the treatment of unwanted facial hair in women using TrichoScan.
Eur J Dermatol (2008) 18 (1): 65-70  Download

R Hoffmann  (comment to Van Neste)
TrichoScan, a GCP-validated tool to measure hair growth.
JEADV (2008) 22, 101–136  Download

N Lengg, Heidecker B, Seifert B, RM Trüeb
Dietary supplement increases anagen hair rate in women with telogen effluvium: results of a double-blind, placebo-controlled trial.
Therapy (2007) 4, 59–65

D Van Neste, RM Trüeb
Critical study of hair growth analysis with computer-assisted methods.
JEADV (2006) 20, 578–583

U Blume-Peytavi, C Kunte, A Krisp, N Garcia Bartels, U Ellwanger, R Hoffmann
Comparison of the efficacy and safety of topical minoxidil and topical alfatradiol in the treatment of androgenetic alopecia in women.
JDDG (2007) 5 (5): 391-395 Download

R Hoffmann and D Van Neste
Recent Findings with Computerized Methods for Scalp Hair Growth Measurements.
J Investig Dermatol Symp Proc 2005 Dec;10(3):285-8.

R Hoffmann
TrichoScan: What Is New?
Dermatology (2005) 211:54–62

A J Chamberlain and R Dawber
Methods of evaluating hair growth.
Australasian Journal of Dermatology (2003) 44:10–18

R Hoffmann
TrichoScan: A Novel Tool For The Analysis of Hair Growth in vivo.
J Investig Dermatol Symp Proc. 2003 Jun;8(1):109-15.

R Hoffmann
TrichoScan: Ein neues Werkzeug für die digitale Haarzählung.
Hautarzt (2002) 53:798–804 Download

R Hoffmann
TrichoScan: combining epiluminescence microscopy with digital image analysis for the measurement of hair growth in vivo.
Eur J Dermatol (2001) 11: 362-368


Publications about hair loss and the tools to monitor hair loss 

  • de Lacharriere-O; Deloche-C; Misciali-C; Piraccini-BM; Vincenzi-C; Bastien-P; Tardy-I; Bernard-BA; Tosti-A: Hair diameter diversity: a clinical sign reflecting the follicle miniaturization. Arch Dermatol. MAY 2001; 137 (5):641-646
  • Van-Neste-D; Fuh-V; Sanchez-Pedreno-P; Lopez-Bran-E; Wolff-H; Whiting-D; Roberts-J; Kopera-D; Stene-JJ; Calvieri-S; Tosti-A; Prens-E; Guarrera-M; Kanojia-P; He-W; Kaufman-KD: Finasteride increases anagen hair in men with androgenetic alopecia. BRITISH-JOURNAL-OF-DERMATOLOGY. OCT 2000; 143 (4) : 804-810
  • Gehring-W; Gloor-M: Das Phototrichogramm als Verfahren zur Beurteilung haarwachstumsfördernder Präparate am Beispiel einer Kombination von Hirsefruchtextrakt, L-Cystin und Calciumpantothenat. H+G (2000) 75:397-496
  • Whiting-DA; Waldstreicher-J; Sanchez-M; Kaufman-KD: Measuring reversal of hair miniaturization in androgenetic alopecia by follicular counts in horizontal sections of serial scalp biopsies: Results of finasteride 1 mg treatment of men and postmenopausal women. JOURNAL-OF-INVESTIGATIVE-DERMATOLOGY-SYMPOSIUM-PROCEEDINGS. DEC 1999; 4 (3) : 282-284
  • Price-VH; Menefee-E; Strauss-PC: Changes in hair weight and hair count in men with androgenetic alopecia, after application of 5% and 2% topical minoxidil, placebo, or no treatment. JOURNAL-OF-THE-AMERICAN-ACADEMY-OF-DERMATOLOGY. NOV 1999; 41 (5) Part 1 : 717-721
  • Price-VH; Menefee-E; Strauss-PC: Changes in hair weight and hair count in men with androgenetic alopecia, after application of 5% and 2% topical minoxidil, placebo, or no treatment. J-Am-Acad-Dermatol. 1999 Nov; 41
  • Van-Neste-D: Human scalp hair growth and loss evaluation methods: is there simple and reliable method? Exp-Dermatol. 1999 Aug; 8(4): 299-301
  • Gruber-DM; Berger-UE; Sator-MO; Horak-F; Huber-JC: Computerized assessment of facial hair growth. FERTILITY-AND-STERILITY. OCT 1999; 72 (4) : 737-739
  • Hutchinson-PE; Thompson-JR: The size and form of the medulla of human scalp hair is regulated by the hair cycle and cross-sectional size of the hair shaft. BRITISH-JOURNAL-OF-DERMATOLOGY. MAR 1999; 140 (3) : 438-445
  • Guarrera-M; Semino-MT; Rebora-A: Quantitating hair loss in women: A critical approach. DERMATOLOGY-. 1997; 194 (1) : 12-16
  • Hutchinson-PE; Thompson-JR: The cross-sectional size and shape of human terminal scalp hair. BRITISH-JOURNAL-OF-DERMATOLOGY. FEB 1997; 136 (2) : 159-165
  • Hayashi-S; Miyamoto-I; Takeda-K: Measurement of human hair growth.BIOENGINEERING-OF-THE-SKIN-SKIN-SURFACE-IMAGING-AND-ANALYSIS. 1997; : 241-250
  • Van-Neste-DJ; Rushton-DH: Hair problems in women. Clin-Dermatol. 1997 Jan-Feb; 15(1): 113-25
  • Van Neste DJJ, De Brouwer B, De Coster W: The Phototrichogram: Analysis of Some Technical Factors of Variation. Skin Pharmacol 1994; 7:67-72
  • Van Neste DJJ: Hair Growth Evaluation in Clinical Dermatology (Editorial) Dermatology (1993) 187:233-234
  • Alcaraz-MV; Villena-A; Perez-de-Vargas-I: Quantitative study of the human hair follicle in normal scalp and androgenetic alopecia. J-Cutan-Pathol. 1993 Aug; 20(4): 344-9
  • Peereboom-Wynia-JD; Beek-CH; Mulder-PG; Stolz-E: The trichogram as a prognostic tool in alopecia areata. Acta-Derm-Venereol. 1993 Aug; 73(4): 280-2
  • Rushton-DH; de-Brouwer-B; de-Coster-W; van-Neste-DJ: Comparative evaluation of scalp hair by phototrichogram and unit area trichogram analysis within the same subjects. Acta-Derm-Venereol. 1993 Apr; 73(2): 150-3
  • Hayashi-S; Miyamoto-I; Takeda-K: Measurement of human hair growth by optical microscopy and image analysis. Cosmetics Laboratory, Kanebo Ltd, Odawara, Japan. Br-J-Dermatol. 1991 Aug; 125(2): 123-9
  • Rushton-DH; Ramsay-ID; Norris-MJ; Gilkes-JJ. Natural progression of male pattern baldness in young men. Clin-Exp-Dermatol. 1991 May; 16(3): 188-92
  • Price-VH; Menefee-E: Quantitative estimation of hair growth. I. androgenetic alopecia in women: effect of minoxidil. J-Invest-Dermatol. 1990 Dec; 95(6): 683-7
  • Rushton-DH; Ramsay-ID; James-KC; Norris-MJ; Gilkes-JJ: Biochemical and trichological characterization of diffuse alopecia in women. Br-J-Dermatol. 1990 Aug; 123(2): 187-97
  • Peereboom-Wynia-JD; van-der-Willigen-AH; van-Joost-T; Stolz-E: The effect of cyproterone acetate on hair roots and hair shaft diameter in androgenetic alopecia in females. Acta-Derm-Venereol. 1989; 69(5): 395-8
  • Rushton-DH; Unger-WP; Cotterill-PC; Kingsley-P; James-KC: Quantitative assessment of 2% topical minoxidil in the treatment of male pattern baldness. Clin-Exp-Dermatol. 1989 Jan; 14(1): 40-6
  • Pelfini-c, Calligaro-A: Some Notes on the Evalutaion of Hair Growth by Means of Morphometric Computerized Analysis. J Appl. Cosmetol. 1986; 4: 67-76
  • Gibbons-RD; Fiedler-Weiss-VC: Computer-aided quantification of scalp hair. Dermatol-Clin. 1986 Oct; 4(4): 627-40
  • Guarrera M, Ciulla MP: A Qunatitative Evaluation of Hair Loss: The Phototrichogram. J Appl. Cosmetol. 1986; 4: 66-66
  • Mortimer-CH; Rushton-H; James-KC: Effective medical treatment of common baldness in women. Clin-Exp-Dermatol. 1984 Jul; 9(4): 342-50
  • Rushton-H; James-KC; Mortimer-CH: The unit area trichogram in the assessment of androgen-dependent alopecia. Br-J-Dermatol. 1983 Oct; 109(4): 429-37
  • Jackson-D, Church-RE, Ebling-FJ: Hair Diameter in Female Baldness. Br. J. Derm. (1972) 87:361-367
  • Barman-JM; Astore-I; Pecoraro-V: The Normal Trichogram of the Adult. Journal of Investigative Dermatology, 44:233-236